Biomonitoring of arsenic, lead, manganese and mercury in hair from a presumably exposed Uruguayan child population.

IF 1.9 4区医学 Q3 BIOCHEMICAL RESEARCH METHODS Bioanalysis Pub Date : 2024-01-01 Epub Date: 2023-11-15 DOI:10.4155/bio-2023-0157

Fiorella Iaquinta, Ignacio Machado

引用次数: 0

Abstract

Aim: To perform an exposure assessment of arsenic, manganese, mercury and lead levels in hair samples from children from poor neighborhoods. Materials & methods: A total of 38 Caucasian children were recruited with the consent of their parents or tutors. Determinations were performed by atomic absorption spectrometry. Results & conclusion: Results were 0.045-0.12 μg/g^-1 (arsenic), 0.56-2.05 μg/g^-1 (manganese) and 0.34-27.8 μg/g^-1 (lead). Lead results did not correlate with those previously reported in blood from the same individuals, suggesting that hair is not useful for exposure assessment of this contaminant. Mercury was determined for the first time in Uruguayan children showing levels <0.083 μg/g^-1. Results revealed low-to-moderate metal exposure, except for some high lead findings.

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乌拉圭儿童头发中砷、铅、锰和汞的生物监测。

目的:对贫困社区儿童头发样本中的砷、锰、汞和铅水平进行暴露评估。材料与方法:经父母或导师同意，共招募38名白人儿童。采用原子吸收光谱法测定。结果与结论:砷含量为0.045 ~ 0.12 μg/g-1，锰含量为0.56 ~ 2.05 μg/g-1，铅含量为0.34 ~ 27.8 μg/g-1。铅的检测结果与先前报道的同一个人的血液中铅的检测结果没有相关性，这表明头发对这种污染物的暴露评估没有用处。首次在乌拉圭儿童中检测出汞水平为-1。结果显示低至中度的金属暴露，除了一些高铅的发现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Bioanalysis BIOCHEMICAL RESEARCH METHODS-CHEMISTRY, ANALYTICAL

CiteScore

3.30

自引率

16.70%

发文量

审稿时长

2 months

期刊介绍： Reliable data obtained from selective, sensitive and reproducible analysis of xenobiotics and biotics in biological samples is a fundamental and crucial part of every successful drug development program. The same principles can also apply to many other areas of research such as forensic science, toxicology and sports doping testing. The bioanalytical field incorporates sophisticated techniques linking sample preparation and advanced separations with MS and NMR detection systems, automation and robotics. Standards set by regulatory bodies regarding method development and validation increasingly define the boundaries between speed and quality. Bioanalysis is a progressive discipline for which the future holds many exciting opportunities to further reduce sample volumes, analysis cost and environmental impact, as well as to improve sensitivity, specificity, accuracy, efficiency, assay throughput, data quality, data handling and processing. The journal Bioanalysis focuses on the techniques and methods used for the detection or quantitative study of analytes in human or animal biological samples. Bioanalysis encourages the submission of articles describing forward-looking applications, including biosensors, microfluidics, miniaturized analytical devices, and new hyphenated and multi-dimensional techniques. Bioanalysis delivers essential information in concise, at-a-glance article formats. Key advances in the field are reported and analyzed by international experts, providing an authoritative but accessible forum for the modern bioanalyst.