Psoriasis flares after COVID-19 vaccination: adherence to biologic therapy reduces psoriasis exacerbations: a case-control study.

Martina Burlando, Astrid Herzum, Emanuele Cozzani, Aurora Parodi
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引用次数: 2

Abstract

This study aimed to evaluate if patients under biologics have a lower risk of psoriasis flares after coronavirus disease 2019 (COVID-19) vaccination than other psoriatic patients. Of 322 recently vaccinated patients admitted for psoriasis at the Dermatological Psoriasis Unit during January and February 2022, 316 (98%) had no psoriasis flares after COVID-19 vaccination (79% under biologic treatment, 21% not biologically treated) and 6 (2%) presented psoriasis flares after COVID-19 vaccination (33.3% under biologic treatment, 66.6% not biologically treated). Overall, psoriasis patients under biologic treatment, developed fewer psoriasis flares after COVID-19 vaccination (33.3%), than patients not under biologic treatment (66.6%) (p=0.0207; Fisher's exact test).

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COVID-19疫苗接种后牛皮癣发作:坚持生物治疗可减少牛皮癣恶化:一项病例对照研究
本研究旨在评估接种生物制剂的患者在2019冠状病毒病(COVID-19)疫苗后患牛皮癣的风险是否低于其他牛皮癣患者。在2022年1月至2月期间,在皮肤科牛皮癣部门收治的322名最近接种牛皮癣疫苗的患者中,316(98%)在接种COVID-19疫苗后没有牛皮癣发作(79%接受生物治疗,21%未接受生物治疗),6(2%)在接种COVID-19疫苗后出现牛皮癣发作(33.3%接受生物治疗,66.6%未接受生物治疗)。总体而言,接受生物制剂治疗的牛皮癣患者在COVID-19疫苗接种后出现的牛皮癣斑块(33.3%)少于未接受生物制剂治疗的患者(66.6%)(p=0.0207;费雪精确检验)。
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来源期刊
CiteScore
3.70
自引率
3.70%
发文量
29
审稿时长
8 weeks
期刊介绍: Clin Exp Vaccine Res, the official English journal of the Korean Vaccine Society, is an international, peer reviewed, and open-access journal. It covers all areas related to vaccines and vaccination. Clin Exp Vaccine Res publishes editorials, review articles, special articles, original articles, case reports, brief communications, and correspondences covering a wide range of clinical and experimental subjects including vaccines and vaccination for human and animals against infectious diseases caused by viruses, bacteria, parasites and tumor. The scope of the journal is to disseminate information that may contribute to elaborate vaccine development and vaccination strategies targeting infectious diseases and tumors in human and animals. Relevant topics range from experimental approaches to (pre)clinical trials for the vaccine research based on, but not limited to, basic laboratory, translational, and (pre)clinical investigations, epidemiology of infectious diseases and progression of all aspects in the health related issues. It is published printed and open accessed online issues (https://ecevr.org) two times per year in 31 January and 31 July. Clin Exp Vaccine Res is linked to many international databases and is made freely available to institutions and individuals worldwide
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