Bone Remodelling of the Proximal Femur After Hip Revision with a Metaphyseal-Fixation Femoral Stem Component.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2023-01-01 DOI:10.2147/TCRM.S393876
Zhijie Li, Mengnan Li, Xiaowei Yao, Bo Liu, Sikai Liu, Zeming Liu, Binquan Zhang, Yongtai Han
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Abstract

Background: Whether hip revision with a metaphyseal-fixation femoral stem component can restore the bone mass of the proximal femur remains unclear. The aims of this study were to identify whether the bone mineral density (BMD) of the proximal femur increases following hip revision with a metaphyseal-fixation femoral stem and to identify the factors associated with BMD recovery.

Methods: This was a retrospective study involving 36 patients who underwent hip arthroplasty with a metaphyseal-diaphyseal fixation stem (standard length stem) and had indications for hip revision, which was performed with a proximal press-fit short-stem prosthesis for each patient. Dual-energy X-ray absorptiometry (DEXA) was used to obtain, evaluate, and compare the BMD at baseline and one year and two years postoperatively. The proximal femur was divided into several independent areas according to the Gruen zone (Gruen 1 to Gruen 7 from the greater trochanter counterclockwise to the lesser trochanter). Logistic regression analyses were used to assess potential factors significantly associated with an increase in BMD.

Results: An increased BMD was obviously identified in the proximal femur. Two years after the surgery, the BMD of the Gruen 1, Gruen 2, Gruen 6, and Gruen 7 areas had increased by 22.6%, 12.6%, 16.2% and 24.2%, respectively, relative to baseline. Three independent risk factors associated with bone mineral density recovery were identified: age (OR=1.100, 95% CI=1.005-1.203, P=0.038), osteoporosis (OR=14.921, 95% CI=1.223-182.101, P=0.034) and fair to poor hip function (OR=13.142, 95% CI=1.024-168.582, P=0.048).

Conclusion: This study confirms that metaphyseal-fixation stem hip revision can indeed help restore bone mass in the proximal femur, especially in the Gruen 1, Gruen 2, Gruen 6 and Gruen 7 zones. It was also found that advanced age, osteoporosis, and fair to poor hip joint function were three important risk factors affecting the recovery of proximal femur bone mass after surgery.

Trial registration: Retrospectively registered.

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股骨干骺端固定假体髋关节翻修后股骨近端骨重建。
背景:采用干骺端固定股骨干假体进行髋关节翻修是否能恢复股骨近端骨量尚不清楚。本研究的目的是确定股骨近端骨矿物质密度(BMD)是否在股骨干骺端固定髋关节翻修后增加,并确定与BMD恢复相关的因素。方法:这是一项回顾性研究,涉及36例采用干骺端-干骺端固定柄(标准长度柄)进行髋关节置换术并有髋关节翻修指征的患者,每位患者使用近端加压短柄假体进行髋关节翻修。采用双能x线骨密度仪(DEXA)获取、评估和比较基线、术后1年和2年的骨密度。根据Gruen区(Gruen 1 ~ Gruen 7,从大转子逆时针方向至小转子)将股骨近端分成几个独立区域。Logistic回归分析用于评估与骨密度增加显著相关的潜在因素。结果:股骨近端骨密度明显增高。术后2年,gruen1、gruen2、gruen6和gruen7区的骨密度分别较基线增加22.6%、12.6%、16.2%和24.2%。确定了与骨密度恢复相关的三个独立危险因素:年龄(OR=1.100, 95% CI=1.005-1.203, P=0.038)、骨质疏松(OR=14.921, 95% CI=1.223-182.101, P=0.034)和髋关节功能差(OR=13.142, 95% CI=1.024-168.582, P=0.048)。结论:本研究证实,干骺端固定髋关节翻修确实有助于股骨近端骨量的恢复,特别是在gruen1、gruen2、gruen6和gruen7区。高龄、骨质疏松、髋关节功能一般到较差是影响术后股骨近端骨量恢复的三个重要危险因素。试验注册:回顾性注册。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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