Effect of cerebral microbleeds on hemorrhagic transformation and functional prognosis after intravenous thrombolysis of cerebral infarction

IF 1.3 Q4 CLINICAL NEUROLOGY Brain Hemorrhages Pub Date : 2022-09-01 DOI:10.1016/j.hest.2021.05.004
Jinli Chen , Kamil Duris , Xiaobo Yang
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引用次数: 4

Abstract

Hemorrhagic transformation is a common complication of acute cerebral infarction, and rtPA thrombolytic therapy will increase the risk of hemorrhagic transformation. Cerebral microbleeds (CMBs) have become an important and independent predictor of cerebral hemorrhage. However, it is still controversial whether CMBs increase the risk of intracranial hemorrhage (ICH) and poor prognosis (PFO) after intravenous thrombolysis (IVT) in patients with acute ischemic stroke (AIS).This review summarizes a number of studies on microbleeds in clinical patients, and discusses whether the presence, number, and distribution of CMBs are related to ICH and PFO after IVT in AIS patients, as well as the significance of CMBs in IVT decision-making in AIS.

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脑微出血对脑梗死静脉溶栓术后出血转化及功能预后的影响
出血性转化是急性脑梗死的常见并发症,rtPA溶栓治疗会增加出血性转化的风险。脑微出血(CMBs)已成为脑出血的重要且独立的预测指标。然而,CMBs是否会增加急性缺血性卒中(AIS)患者静脉溶栓(IVT)后颅内出血(ICH)和预后不良(PFO)的风险仍存在争议。本文综述了多项关于临床患者微出血的研究,探讨了CMBs的存在、数量和分布是否与AIS患者IVT后脑出血和PFO有关,以及CMBs在AIS患者IVT决策中的意义。
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来源期刊
Brain Hemorrhages
Brain Hemorrhages Medicine-Surgery
CiteScore
2.90
自引率
0.00%
发文量
52
审稿时长
22 days
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