{"title":"Scanning electron microscopy studies of erythrocytes in Huntington's Disease","authors":"William R. Markesbery , D. Allan Butterfield","doi":"10.1016/0006-291X(77)90215-7","DOIUrl":null,"url":null,"abstract":"<div><p>Scanning electron microscopic study of unmanipulated erythrocytes from Huntington's Disease (HD) patients disclosed an increased number of stomatocytes compared to controls. This morphological alteration may reflect a membrane abnormality and supports our previous electron spin resonance results (<span>Butterfield <span><math><mtext>et al</mtext></math></span>, Nature (1977)</span><span><math><mtext>267</mtext></math></span>, 453–455) which suggests that HD may have diffuse membrane involvement.</p></div>","PeriodicalId":8779,"journal":{"name":"Biochemical and biophysical research communications","volume":"78 2","pages":"Pages 560-564"},"PeriodicalIF":2.2000,"publicationDate":"1977-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0006-291X(77)90215-7","citationCount":"43","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biochemical and biophysical research communications","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0006291X77902157","RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 43
Abstract
Scanning electron microscopic study of unmanipulated erythrocytes from Huntington's Disease (HD) patients disclosed an increased number of stomatocytes compared to controls. This morphological alteration may reflect a membrane abnormality and supports our previous electron spin resonance results (Butterfield , Nature (1977), 453–455) which suggests that HD may have diffuse membrane involvement.
期刊介绍：
Biochemical and Biophysical Research Communications is the premier international journal devoted to the very rapid dissemination of timely and significant experimental results in diverse fields of biological research. The development of the "Breakthroughs and Views" section brings the minireview format to the journal, and issues often contain collections of special interest manuscripts. BBRC is published weekly (52 issues/year).Research Areas now include: Biochemistry; biophysics; cell biology; developmental biology; immunology
; molecular biology; neurobiology; plant biology and proteomics
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