{"title":"N-Methyly Isatin β-thiosemicarbazone-Copper Complex Inhibits RNA-Dependent DNA Polymerase but not Ribunuclease rous Sarcoma Virus","authors":"Lu-Hai Wang, Warren Levinson","doi":"10.1016/0006-3061(78)80007-6","DOIUrl":null,"url":null,"abstract":"<div><p><em>N</em>-Methyl isatin β-thiosemicarbazone-copper complex inhibits the RNA-dependent DNA polymerase activity of Rous sarcoma virus (RSV), but not its ribonuclease H. activity. In addition, bovine pancreatic RNase and DNase are not inhibited by the complex.</p></div>","PeriodicalId":9177,"journal":{"name":"Bioinorganic chemistry","volume":"8 6","pages":"Pages 535-540"},"PeriodicalIF":0.0000,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0006-3061(78)80007-6","citationCount":"5","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioinorganic chemistry","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0006306178800076","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 5
Abstract
N-Methyl isatin β-thiosemicarbazone-copper complex inhibits the RNA-dependent DNA polymerase activity of Rous sarcoma virus (RSV), but not its ribonuclease H. activity. In addition, bovine pancreatic RNase and DNase are not inhibited by the complex.
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