Alpha-feto protein in the serum of patients with primary gastric cancer and liver metastases.

Acta hepato-gastroenterologica Pub Date : 1979-06-01
E Libman, J Lemberger, J Kollin
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Abstract

The authors presented a patient with primary gastric cancer and liver metastases. They permanently observed the AFP concentrations before, during and after cytostatic therapy. At the same time they examined possible sites of AFP production. It is supposed that AFP neo-synthesis takes place in the secondary site with participation of altered liver cells. In such cases it is important to watch the AFP values, and this is also necessary when the primary source of the secondary liver cancer is not known. Cytostatic drugs act only in a palliative way i.e. AFP concentrations drop to a lower level and the patient feels temporarily better.

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原发性胃癌及肝转移患者血清中甲胎蛋白的变化。
作者报告了一例原发性胃癌合并肝转移的患者。他们在细胞抑制剂治疗前、期间和之后永久观察AFP浓度。同时,他们检查了AFP可能产生的地点。据推测,AFP的新合成发生在次要位点,并有改变的肝细胞参与。在这种情况下,观察AFP值是很重要的,当继发性肝癌的主要来源不清楚时,这也是必要的。细胞抑制药物仅以缓和方式起作用,即甲胎蛋白浓度下降到较低水平,患者暂时感觉好转。
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