Factors Predicting Avascular Necrosis After Closed Reduction and Internal Fixation of Displaced Subcapital Fractures of the Hip

Ron Gurel
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Abstract

Background: The main complications following closed reduction and internal fixation of displaced intracapsular femur fractures (DICFF) are avascular necrosis (AVN) and nonunion. Little is known about the factors that predict these complications. The purpose of this study was to assess the clinical and radiological risk factors of failure following closed reduction and internal fixation of DICFF among non-elderly patients. Methods: We retrospectively reviewed patients under the age of 65 years who underwent closed reduction and internal fixation of DICFF in our center from January 2007 to January 2018. The extracted data included baseline characteristics and the fixation method. Postoperative radiographs were obtained during follow-up visits in order to evaluate complications, such as AVN and nonunion. Results: In total, 90 patients were included in the study, with a mean follow-up of 6.5 years. Garden III fractures were associated with significantly lower rates of AVN (odds ratio [OR] = 0.304, 95%confidence interval [CI]: 0.101-0.916) compared to Garden IV fractures. Neutral and varus reduction positions had significantly higher rates of AVN (OR = 7.182, 95%CI: 1.951- 26.446) and (OR= 5.560, 95%CI: 1.130-27.351), respectively, compared to the valgus position. Longer surgery procedures were associated with a higher risk of AVN (OR = 1.018, 95%CI: 1.006-1.031). Conclusions: Both varus and neutral reduction positions as well as Garden IV classification served as predictive factors for failure following closed reduction and internal fixation of DICFF. The type of fixation (CCS vs Targon plate) and the Pauwel angle had no significant effect on the rates of AVN or nonunion following fracture reduction.
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移位性髋下骨折闭合复位内固定后缺血性坏死的预测因素
背景:移位性股骨囊内骨折(DICFF)闭合复位内固定后的主要并发症是无血管坏死(AVN)和骨不连。我们对预测这些并发症的因素知之甚少。本研究的目的是评估非老年患者DICFF闭合复位内固定失败的临床和影像学危险因素。方法:回顾性分析2007年1月至2018年1月在本中心接受闭合复位内固定的65岁以下患者。提取的数据包括基线特征和固定方法。术后x线片在随访期间获得,以评估并发症,如AVN和不愈合。结果:共纳入90例患者,平均随访6.5年。Garden III型骨折与Garden IV型骨折相比,AVN发生率明显降低(优势比[OR] = 0.304, 95%可信区间[CI]: 0.101-0.916)。中立位和内翻复位位AVN发生率显著高于外翻位(OR= 7.182, 95%CI: 1.951 ~ 26.446)和(OR= 5.560, 95%CI: 1.130 ~ 27.351)。手术时间越长,AVN发生的风险越高(OR = 1.018, 95%CI: 1.006-1.031)。结论:内翻位、中立位复位及Garden IV分型是DICFF闭合复位内固定失败的预测因素。固定类型(CCS vs Targon钢板)和Pauwel角度对骨折复位后AVN或不愈合的发生率无显著影响。
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