Predicting Algorithms and Complexity in RNA Structure Based on BHG

Zhendong Liu, Yurong Yang, Xinrong Lv, Dongyan Li, Xi Chen, Xiaofeng Li
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Abstract

It is a computing mode of basin hopping graph in RNA folding structural prediction including pseudoknots. We investigate the computing algorithm in RNA folding structural prediction based on extended structure and basin hopping graph. This study presents predicting algorithm based on extended structure, also presents an improved computing algorithm based on basin hopping graph, they are attractive approachs in RNA folding structural prediction. Many experiments have been implemented in Rfam14.2 database and PseudoBase database, the experimental results show our two algorithms are efficiently and accurately than other existing algorithm.
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基于BHG的RNA结构预测算法及复杂度
它是包含假结的RNA折叠结构预测中的一种盆跳图计算模式。研究了基于扩展结构和盆跳图的RNA折叠结构预测的计算算法。本文提出了基于扩展结构的预测算法,以及基于盆跳图的改进计算算法,它们是RNA折叠结构预测中有吸引力的方法。在Rfam14.2数据库和PseudoBase数据库中进行了大量的实验,实验结果表明,这两种算法比现有的算法更高效、准确。
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