Evaluation of cerium doped lutetium oxyorthosilicate (LSO) scintillation crystals for PET

F. Daghighiam, P. Shenderov, K. Pentlow, M. Graham, C. Melcher, J. Schweitzer
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引用次数: 55

Abstract

A new scintillation crystal, cerium-doped lutetium oxyorthosilicate (LSO), was recently discovered, with light intensity 75% of NaI(Tl), scintillation decay time of 12 ns (30%) and 42 ns (70%), effective Z of 66, and density of 7.4 g/cc. The fast decay time and scintillation light output of LSO are superior to those of bismuth germanate (BGO) for positron emission tomography (PET) and the stopping power of LSO for 511 keV photons is only slightly lower than that of BGO. The authors directly compared the detection characteristics relevant to PET applications of small crystals of LSO (2*2*10 mm) with those of BGO. The energy resolution at 511 keV was 12% FWHM for LSO and two to three times wider for BGO. The coincidence timing of two opposing crystals, using a position sensitive photomultiplier tube (PMT) (Hamamatsu R2486), were 1.4 ns FWHM for LSO and more than three times higher for BGO. Using a fast PMT (Hamamatsu R3177), coincidence timing for LSO yielded 0.46 ns FWHM. These crystals are being used to simulate a small-scale PET scanner and to investigate its imaging performance.<>
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用于PET的掺铈氧化硅酸镥(LSO)闪烁晶体的评价
最近发现了一种新的闪烁晶体,掺铈氧化硅酸镥(LSO),其光强为NaI(Tl)的75%,闪烁衰减时间分别为12 ns(30%)和42 ns(70%),有效Z为66,密度为7.4 g/cc。在正电子发射断层扫描(PET)中,LSO的快速衰减时间和闪烁光输出优于锗酸铋(BGO), LSO对511 keV光子的阻挡能力仅略低于BGO。作者直接比较了LSO (2*2*10 mm)小晶体与BGO的PET应用相关检测特性。511 keV时,LSO的能量分辨率是FWHM的12%,BGO的能量分辨率是FWHM的两到三倍。使用位置敏感光电倍增管(PMT) (Hamamatsu R2486),两个对立晶体的重合时间为LSO的1.4 ns FWHM, BGO的3倍以上。使用快速PMT (Hamamatsu R3177), LSO的重合时序产生0.46 ns FWHM。这些晶体被用来模拟小型PET扫描仪,并研究其成像性能
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