Effect of gabapentin on postoperative pain control after a cesarean delivery: a pilot randomized controlled trial

Abstract

Background: Opioid dependence has risen dramatically and is becoming more common in pregnant women. Finding adjunct methods to reduce the need for postoperative opioid pain medications is needed. The objective of this pilot trial was to evaluate if administration of gabapentin after cesarean delivery would decrease postoperative opiate requirements and pain scores. Methods: This was a pilot, triple-blind, placebo-controlled, randomized trial. Women undergoing a non-emergent repeat cesarean delivery who only planned to bottle feed The primary outcome was opiate consumption in the acute postoperative period. pain that were converted to morphine equivalents for statistical analysis. The secondary outcomes assessed included pain scores and events.