Variability of the relative corpus callosum cross sectional area between dyslexic and normally developed brains

Abstract

Minicolumnar disturbance is a common feature to both dyslexic and autistic brains. This paper is motivated by the persistent need to investigate the effect of minicolumnar disturbance on the magnetic resonance images of the brain. This will serve as a preliminary step to develop a non-invasive methodology to discriminate between the diseases based on the MRI findings. In this paper, we investigate the variability of the ratio between the corpus callosum cross sectional area and the total brain intracranial volume between two groups; a group of dyslexic patients and another group of normal controls. The results show that this ratio differs significantly between the two groups and that it can be used as a discriminatory feature between dyslexic brains and typically developed ones.