The clinical case of a combined new coronavirus infection and whooping cough in an unvaccinated child

Yura Konstantinova, I. Babachenko, S. Kharit, E. I. Bobova, M. Y. Ioffe
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Abstract

   Whooping cough remains a life-threatening infection, especially for unvaccinated young children. The article describes a case of severe and non-smooth course of whooping cough in an unvaccinated girl of 4 months of life from the family hearth of whooping cough and COVID-19. There were cases of COVID-19 and whooping cough in adults in the family, occurring under the mask of a mild respiratory infection, not verified before they were detected in a child and did not require hospitalization. The combined course of two infectious diseases COVID-19 and whooping cough in a 4-monthold unvaccinated girl contributed to the prolongation of the duration of whooping cough, prolonged release of SARS-COV-2 RNA, the late appearance of hematological changes typical of whooping cough, the development of respiratory delays and re-hospitalization of a patient with prolonged respiratory support. In the context of the COVID-19 pandemic, the coverage of routine vaccination has significantly decreased, as a result of which children of the first years of life have become more vulnerable to vaccine-controlled infections, which causes the risk of combined infections.
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一名未接种疫苗的儿童合并新型冠状病毒感染和百日咳的临床病例
百日咳仍然是一种危及生命的感染,特别是对未接种疫苗的幼儿。这篇文章描述了一个来自百日咳和COVID-19家庭的4个月大的未接种疫苗的女孩的严重和不顺利的百日咳过程。该家庭中有成人COVID-19和百日咳病例,在轻度呼吸道感染的口罩下发生,在儿童中发现之前未经核实,不需要住院治疗。1例4个月大未接种疫苗的女童,两种传染病COVID-19和百日咳的联合病程导致百日咳持续时间延长、SARS-COV-2 RNA释放时间延长、百日咳典型血液学改变出现较晚、出现呼吸延迟和延长呼吸支持再次住院。在2019冠状病毒病大流行的背景下,常规疫苗接种的覆盖率大幅下降,因此,一岁以下的儿童更容易受到疫苗控制的感染,从而导致合并感染的风险。
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