Load sensitive mock circulatory system for left ventricular assist device controller evaluation and development

Jonathon L. Williams, J. Antaki, J. Boston, S. L. Williams, J. Woodard, P. Miller, R. Kormos
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引用次数: 14

Abstract

A mock circulatory system (MCS) capable of simulating the principal clinical hemodynamics that influence left ventricular assist device (LVAD) timing has been constructed. The MCS includes lumped compliance and resistance components, polyurethane trileaflet valves, and a voice-coil actuated piston pump to simulate left ventricular pumping action. The novelty of this system is its ability to mimic left ventricular pressure-volume relationships based upon a supplied time-varying elastance. The MCS provides a load-sensitive, "bench-top" simulation of the natural heart and systemic circulation on which automatic control algorithms for LVAD's can be developed.<>
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负荷敏感模拟循环系统左室辅助装置控制器的评估与开发
一个模拟循环系统(MCS)能够模拟影响左室辅助装置(LVAD)定时的主要临床血流动力学。MCS包括集总顺应性和阻力组件,聚氨酯三叶阀和音圈驱动柱塞泵,以模拟左心室泵送动作。该系统的新颖之处在于它能够根据提供的时变弹性模拟左心室压力-容积关系。MCS提供了负载敏感的自然心脏和体循环的“台式”模拟,在此基础上可以开发LVAD的自动控制算法。
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