CALCIUM PYROPHOSPHATE DIHYDRATE DEPOSITION DISEASE OF ELBOW WITH ULNAR NERVE NEUROPATHY: A CASE REPORT

Sunil Panta, Sushil Thapa, R. Thapa, K. Paudel, Prajeeta Bhandari
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Abstract

Crystal deposition disorders are one of the causes of inflammatory arthropathy. A rare variety of this disorder is Calcium Pyrophosphate Dihydrate deposition disease. It is usually seen in the elderly and progresses as calcifications in and around the joint i.e. Chondrocalcinosis with repeated synovitis leading to degenerative changes of large and unusual or non-weight-bearing joints. It is a case report of 43 years housewife with a gradually enlarging mass at posteromedial aspect of the left elbow with ulnar nerve weakness for 1 year. Radiographs revealed degenerative joint with periarticular calcifications. The electrodiagnostic test showed ulnar nerve demyelination and axonal neuropathy. Surgical excision with decompression of ulnar nerve was done. Histopathology revealed features consistent with Pseudogout. Subsequent follow-up resulted in improvement of nerve function with no clinicoradiological evidence of recurrence. So, degenerative changes with periarticular calcifications in non-weight-bearing joints should be suspected for pseudogout. It may be associated with compressive neuropathy.
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肘部二水焦磷酸钙沉积病合并尺神经病变1例
晶体沉积紊乱是炎性关节病的病因之一。这种疾病的一个罕见的变种是焦磷酸钙二水合物沉积病。它通常见于老年人,进展为关节内部和周围的钙化,即软骨钙化症伴反复滑膜炎,导致大而不寻常或不承重的关节退行性改变。本文报告一例43岁的家庭主妇,左肘后内侧有逐渐增大的肿块并伴有尺神经无力1年。x线片显示退行性关节伴关节周围钙化。电诊断结果显示尺神经脱髓鞘及轴索神经病变。手术切除尺神经减压。组织病理学显示的特征与伪out相符。随后的随访显示神经功能改善,无复发的临床放射学证据。因此,非负重关节的退行性改变伴关节周围钙化应怀疑为假性关节脱位。它可能与压缩性神经病变有关。
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