Persistence in humans of antibody after immunization with four alphavirus vaccines.

Asian journal of infectious diseases Pub Date : 1979-09-01
J L DeMeio, A N DeSanctis, W J Thomas
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Abstract

Immunization with attenuated VEE virus vaccine resulted in persistence of neutralizing antibody for 12 years. Immunization with inactivated WEE vaccine converted 83% of the subjects, killed EEE vaccine converted 27% and killed Chikungunya vaccine induced no significant titers. Antibody formed as a result of immunization with inactivated vaccines was of short duration, i.e. less than 1 year. Attenuated VEE was responsible for some heterologous antibody rises to the other three alphaviruses. Among the inactivated vaccines WEE and Chikungunya vaccines produced one heterologous rise each to EEE virus.

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四种甲病毒疫苗免疫后人体内抗体的持久性。
用VEE病毒减毒疫苗免疫可使中和抗体持续12年。灭活WEE疫苗的免疫转换率为83%,灭活EEE疫苗的转换率为27%,灭活基孔肯雅疫苗的免疫转换率无显著性变化。用灭活疫苗免疫后形成的抗体持续时间短,即少于1年。减毒后的VEE对其他三种甲病毒产生了一些异源抗体。在灭活疫苗中,WEE和基孔肯雅疫苗对EEE病毒各产生一个异源上升。
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Relation of colonial morphologies of strain of Streptococcus pneumoniae in soft-agar to the encapsulation. Persistence in humans of antibody after immunization with four alphavirus vaccines. An unusual bacterium from a brain abscess. A review of the interactions of infection and nutrition. Comparative hospital and outpatient antibiotic susceptibilities in Honolulu, Hawaii.
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