{"title":"Cytochrome c release caused by Pulsed Electric Fields (PEFs) with different time durations","authors":"Hao-tse Wu, M. Wu, Heng Zou","doi":"10.1109/MMWCST.2012.6238126","DOIUrl":null,"url":null,"abstract":"Multilayer Dielectric Sphere Model (MDSM) is used for analyzing responses of cells to Pulsed Electric Fields (PEFs), and cytochrome c release is significant effect of PEFs when mitochondrial substructures are taken into account. Numerical results of MDSM model explain and verify the reported experimental results on Intracellular Electro-manipulation (IEM). It is proposed that two-step process of cytochrome c release can be implemented by bioelectric impulse effect on mitochondria.","PeriodicalId":150727,"journal":{"name":"The 2012 International Workshop on Microwave and Millimeter Wave Circuits and System Technology","volume":"12 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2012-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The 2012 International Workshop on Microwave and Millimeter Wave Circuits and System Technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/MMWCST.2012.6238126","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Multilayer Dielectric Sphere Model (MDSM) is used for analyzing responses of cells to Pulsed Electric Fields (PEFs), and cytochrome c release is significant effect of PEFs when mitochondrial substructures are taken into account. Numerical results of MDSM model explain and verify the reported experimental results on Intracellular Electro-manipulation (IEM). It is proposed that two-step process of cytochrome c release can be implemented by bioelectric impulse effect on mitochondria.
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