Towards a Bionic Neural Link for Implantable Prosthetics

Xiaoying Li, T.G. Constandinoir, A. Eftekhar, P. Georgiou, C. Toumazoi
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Abstract

This paper presents a biologically-inspired 'silicon neural link', encompassing a neurochemical sensor array, an asynchronous artificial-neural bus and an interleaved biphasic stimulus generator. The proposed system is intended for neuroprosthetic application; employing an array of ISFET-based spiking neurons to convey measured neuronal data across a damaged neural pathway to a target stimulation site. A 48 dB dynamic range is achieved by encoding the neural signal in the time-domain, using accumulating address-events to modulate the biphasic waveform. The electrical stimulation is delivered via a bipolar electrode configuration in a continuous interleave sampling strategy. This has been implemented in a commercially available 035mum CMOS technology.
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一种用于植入式假肢的仿生神经链
本文提出了一种受生物学启发的“硅神经链”,包括一个神经化学传感器阵列,一个异步人工神经总线和一个交错双相刺激发生器。提出的系统用于神经假肢应用;利用一系列基于isfet的尖峰神经元将测量到的神经元数据通过受损的神经通路传递到目标刺激部位。通过在时域对神经信号进行编码,利用累积地址事件调制双相波形,实现了48 dB的动态范围。电刺激通过双极电极配置在连续交错采样策略中传递。这已经在商用的035mum CMOS技术中实现。
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