Beta-adrenergic receptors gene polymorphisms effects on cardiovascular control

Abstract

$\upbeta$-adrenergic receptors ($\upbeta$-ARs) playa pivotal role in the cardiovascular control. Several single nucleotide polymorphisms (SNPs) of $\upbeta$-ARs might influence cardiovascular function. We aimed to explore the associations between four selected $\upbeta$-ARs gene polymorphisms and cardiovascular control related measures in young healthy subjects. We conclude that complex analysis of various cardiovascular characteristics reflecting the strength of cardiac contraction and blood pressure variability can reveal subtle differences in cardiovascular sympathetic nervous control associated with $\upbeta$-ARs polymorphisms.