The effect of drug therapy without volume replacement in experimental traumatic shock. Part I. Phenoxybenzamine and dopamine.

M Lahdensuu, P Rokkanen
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Abstract

The effect of phenoxybenzamine and dopamine on the respiratory and metabolic changes in experimental traumatic shock was examined in 45 rabbits. Phenoxybenzamine caused a more effective release of the peripheral vasoconstriction than dopamine. The effect of these drugs without similar restoration of blood volume was unfavourable. This should be borne in mind when the use of these drugs is meditated in clinical work.

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实验性外伤性休克的药物治疗效果。第一部分:苯氧苄胺和多巴胺。
研究了苯氧苄胺和多巴胺对实验性创伤性休克兔呼吸和代谢变化的影响。苯氧苄胺比多巴胺能更有效地释放外周血管收缩。这些药物没有类似的血容量恢复效果是不利的。在临床工作中考虑使用这些药物时,应牢记这一点。
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