{"title":"Overview of Role of Radionuclides in Scanning the Brain in Health and Disease","authors":"Sanjoy Sanyal","doi":"10.15406/JNSK.2017.06.00211","DOIUrl":null,"url":null,"abstract":"99mTc pertechnetate scan: The pertechnetate (TcO4) ion in technetium (Tc) pertechnetate binds to plasma proteins, quickly moves into the extra-cellular space and distributes itself like the chloride (Cl-) ion in various organs except the normal brain because of the blood brain barrier (BBB). Thus, negligible uptake of the isotope by the normal brain prevents its effective visualisation by isotope scan, unlike other organs [3].","PeriodicalId":106839,"journal":{"name":"Journal of Neurology and Stroke","volume":"117 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2017-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Neurology and Stroke","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15406/JNSK.2017.06.00211","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
99mTc pertechnetate scan: The pertechnetate (TcO4) ion in technetium (Tc) pertechnetate binds to plasma proteins, quickly moves into the extra-cellular space and distributes itself like the chloride (Cl-) ion in various organs except the normal brain because of the blood brain barrier (BBB). Thus, negligible uptake of the isotope by the normal brain prevents its effective visualisation by isotope scan, unlike other organs [3].
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