Does Vitamin D Supplementation have a Positive and Important Response in the Immune System on Covid-19 Pandemic? A Short Critical Analysis

Eliza M Ramos, Francisco J M Reis, Igor Souza, S. L. F. D. Freitas, Matheus Dullius de Lima, Antônio Carlos de Abreu, Hugo Vieira Ramos, E. Araújo, V. Nascimento
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引用次数: 2

Abstract

In recent years, new viruses have emerged and caused pandemics in several countries, making it a global health problem through respiratory infection. This study aims to demonstrate through an analysis of evidence, that vitamin D supplementation in cases of hypovitaminosis D in risk groups induces an increase changes in the immune system due to worsening and, thus, the body becomes conducive to development viral diseases like COVID-19. Therefore, methodological techniques were used in meta-analysis and systematic reviews parallel to the FINER strategy in the selection of the included studies to be used in the construction of this critical analysis. In this study, 05 articles were selected for inclusion in this critical analysis. Vitamin D plays an immune protective role in the body, decreasing the risk of complications in COVID-19. The decrease in immune cells and cytokines can be used as a biomarker in the process of worsening COVID-19.
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补充维生素D是否对Covid-19大流行免疫系统有积极和重要的反应?简短的批判性分析
近年来,出现了新的病毒,并在若干国家造成大流行,通过呼吸道感染成为一个全球性的健康问题。本研究旨在通过证据分析证明,在维生素D缺乏症的风险人群中补充维生素D会导致免疫系统的变化增加,从而使身体更容易发生COVID-19等病毒性疾病。因此,在选择纳入的研究用于构建这一批判性分析时,在荟萃分析和系统综述中使用了与FINER策略平行的方法学技术。在这项研究中,选择了05篇文章纳入这项批判性分析。维生素D在体内具有免疫保护作用,可降低COVID-19并发症的风险。免疫细胞和细胞因子的减少可以作为COVID-19恶化过程中的生物标志物。
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