Short Term Outcome of Percutaneous Coronary Intervention in Anaemic Patients Presenting with Coronary Artery Diseases

Moaz Emad El Din El Saiyed, M. Nassar, Ehab Abd El Lateif El Gendy, S. Badr
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Abstract

Background: Percutaneous coronary intervention (PCI) has been an effective and widely used treatment for patients with coronary artery disease (CAD). The presence of anaemia in critically ill patients undergoing surgical procedures has been associated with worse clinical outcomes. Hence, the current study was conducted to assess short term outcome of percutaneous coronary interventions in anaemic patients presenting with coronary artery diseases. Methods: This prospective observational study enrolled 200 patients who underwent PCI. Patients were classified into 2 groups: anaemic patients and non-anaemic patients. The anaemic patients were furtherly be classified according to severity of anaemia into 3 grades mild anaemia, moderate anaemia, and severe anaemia. All cases were subjected to complete history taking, clinical examination and baseline laboratory tests: including CBC, serum urea and creatinine, cardiac enzymes include serum troponin, CK-MB and standard 12-lead ECG. Results: The mean Heart Rate was statistically significantly higher in the anaemic group as compared with the non-anaemic group. The mean Ejection Fraction was statistically significantly lower in the anaemic group as compared with the non-anaemic group. The percentage of LM affection in the anaemic group was statistically significantly higher as compared with the non-anaemic group. The incidence of arrythmia in the anaemic group was statistically significantly higher as compared with the non-anaemic group. Severe anaemic and low EF% patients were associated with higher incidence of stroke and MI. Conclusions: Patients with baseline anaemia before PCI have a higher incidence of PCI associated complications. Therefore, anaemia could be a predictor of PCI related complications.
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经皮冠状动脉介入治疗伴有冠状动脉疾病的贫血患者的近期疗效
背景:经皮冠状动脉介入治疗(PCI)已成为冠状动脉疾病(CAD)患者有效且广泛应用的治疗方法。在接受外科手术的危重患者中存在贫血与较差的临床结果相关。因此,本研究旨在评估经皮冠状动脉介入治疗伴有冠状动脉疾病的贫血患者的短期疗效。方法:这项前瞻性观察性研究纳入了200例接受PCI治疗的患者。患者分为两组:贫血患者和非贫血患者。根据贫血的严重程度将贫血患者进一步分为轻度贫血、中度贫血和重度贫血3个级别。所有病例均进行了完整的病史记录、临床检查和基线实验室检查:包括CBC、血清尿素和肌酐、心脏酶包括血清肌钙蛋白、CK-MB和标准12导联心电图。结果:贫血组的平均心率明显高于非贫血组。与非贫血组相比,贫血组的平均射血分数有统计学意义上的显著降低。与非贫血组相比,贫血组的LM影响百分比具有统计学意义。与非贫血组相比,贫血组的心律失常发生率有统计学意义。重度贫血和低EF%患者卒中和心肌梗死发生率较高。结论:PCI术前基线贫血患者PCI相关并发症发生率较高。因此,贫血可能是PCI相关并发症的预测指标。
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