A Detailed Review of Pathophysiology, Management and Epidemiology of Acute and Chronic Gout

Arooj Shahid, Ayesha Imran, Syeda Komal Fatima, M. Khan, M. Rehman
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Abstract

Gout is one of the utmost encountered inflammatory arthritis in clinical practice. The purpose of this article is to review the pathophysiology, management and epidemiology of acute and chronic gout. The occurrence of gout throughout the globe has also been documented. Therapies for pain management during gout have also been discussed. Treatment medications of gout can be mainly classified as uricosurics and uric acid synthesis inhibitors, these are discussed in detail in reference to their pharmacokinetics.
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急性和慢性痛风的病理生理学、管理和流行病学的详细综述
痛风是临床上最常见的炎症性关节炎之一。本文的目的是回顾急性和慢性痛风的病理生理,管理和流行病学。痛风在全球范围内的发生也有记录。痛风期间疼痛管理的治疗方法也进行了讨论。痛风的治疗药物主要分为尿酸抑制剂和尿酸合成抑制剂两大类,并就其药代动力学进行了详细的讨论。
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