Genome Based Research in Aquaculture

Somia Liaqat, M. Hussain, M. F. Malik, Asifa J. Aslam
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Abstract

Genome -based technologies are being instigated to manipulate the structure and function of the genome and to identify the genes of interest for genetic modification of economically important species. Genome editing technologies have also been designed for genetic manipulation of aquaculture species to increase production and quality with minimum investment costs. DNA marker technologies are the most widely used genome technologies. DNA fingerprints are used to construct physical maps while genetic maps are based upon meiotic recombination. BAC fingerprinting is the commonly used method for physical mapping. Nextgeneration sequencers revolutionized science and allowed the de-novo whole genome sequencing. QTL mapping has made it possible to identify the genes responsible for a particular trait. Government involvement and better training of aqualturists are direly needed to reinforce the practical implications of genomebased technologies.
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水产养殖基因组研究
以基因组为基础的技术正被用于操纵基因组的结构和功能,并确定对经济上重要物种的基因改造感兴趣的基因。基因组编辑技术也被设计用于水产养殖物种的遗传操纵,以最小的投资成本提高产量和质量。DNA标记技术是目前应用最广泛的基因组技术。DNA指纹图谱用于构建物理图谱,而遗传图谱则基于减数分裂重组。BAC指纹是常用的物理映射方法。下一代测序仪彻底改变了科学,并允许从头进行全基因组测序。QTL定位已经使鉴定特定性状的基因成为可能。迫切需要政府的参与和更好地培训水生动物爱好者,以加强基于基因组的技术的实际意义。
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