Printed Nitrogen-Doped Reduced Graphene Oxide Based Sensor For Uric Acid Detection

Abstract

This paper presents a flexible printed sensor for the accurate detection of uric acid (UA) by a simple chemical route synthesis. The sensitive nanomaterial (N-rGO) was prepared from the dual interaction of 1,4-xylenediamine (XDA) and Graphene oxide (GO) by covalent and $\pi-\pi$ stacking interaction. N-rGO was printed on a flexible polyvinyl chloride (PVC) substrate and analyzed in 0.1 M PBS, pH 7.4 electrolyte for different concentrations of UA. The sensor exhibited a wide segmented linear range of $3-40\times 10^{-5}M$ and $1-8{\mathrm {x}}10^{-3}{\mathrm {M}}$ with a sensitivity of 0.733 ${\mathrm {mAmM^{-1}}}$ and 0.0277 ${\mathrm {mAmM^{-1}}}$ respectively. The 0.0077% standard deviation from 30 consecutive measurements suggests that the sensor exhibits excellent reproducibility. Thus, the presented sensor is an alternative to currently available commercial bulky UA sensors.