The choice of IOP measurement method for assessing the effectiveness of glaucoma surgery

A. A. Vitkov, Kh. Hadiri, T. M. Aghajanyan, A. M. Akimov, I. I. Asinovskova, A. A. Komarov, E. D. Semenov
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Abstract

Purpose of this study — to compare the results of different tonometry methods before surgical treatment of glaucoma and in the early postoperative period.The study was conducted on a group of 50 patients (50 eyes) aged 55 to 80 years with uncompensated primary open-angle glaucoma, who were admitted to in-patient department for glaucoma surgery. Patients were examined using bidirectional applanation tonometry of the cornea performed on Ocular Response Analyzer, pneumotonometry on Canon TX-20P device, and with Icare tonometer. These studies were carried out on the day before the surgery, the next day, and 2 weeks after the operation.Significant differences in tonometry readings were revealed between all tested devices at high intraocular pressure (IOP) levels (before glaucoma surgery). Significant differences were also found in IOP values obtained with Icare tonometer in the central zone of the cornea and in the middle periphery in the nasal and temporal sectors. A significant difference between the indicators remained on the next day after surgery, except for the Icare readings. After two weeks, the tonometric parameters did not differ significantly from each other.Corneal compensated IOP (IOPcc) is the most important tonometric indicator in clinical practice because it takes into account the individual biomechanical characteristics of the patient’s cornea. When examining patients with glaucoma, the IOPcc indicator significantly differed in uncompensated IOP, which is important for determining the correct treatment tactics. When assessing the level of IOP after surgery this trend persisted, indicating a systematic underestimation of IOP level (overestimation of the effect of glaucoma surgery). The reliability of the study is confirmed by the results of measurements on unoperated fellow eyes (control).
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评价青光眼手术疗效的IOP测量方法的选择
本研究的目的是比较青光眼术前和术后早期不同眼压测量方法的结果。研究对象为50例(50只眼),年龄55 ~ 80岁,均为原发性无补偿开角型青光眼,均因青光眼手术入院。采用眼反应分析仪对患者进行双向压平眼压测量,佳能TX-20P眼压测量仪和Icare眼压仪对患者进行眼压测量。这些研究分别在手术前一天、第二天和手术后2周进行。在高眼压(IOP)水平下(青光眼手术前),所有测试装置的眼压读数均有显著差异。用Icare眼压计测得的眼压值在角膜中央区和鼻、颞部的中周区也有显著差异。除Icare读数外,术后第二天各项指标仍有显著差异。两周后,血压计参数之间没有显著差异。角膜代偿IOP (IOPcc)是临床实践中最重要的眼压测量指标,因为它考虑了患者角膜的个体生物力学特征。在检查青光眼患者时,非代偿性IOP的IOPcc指标有显著差异,这对于确定正确的治疗策略很重要。在评估术后IOP水平时,这一趋势持续存在,表明系统性低估了IOP水平(高估了青光眼手术的效果)。该研究的可靠性通过对未手术同伴(对照)的测量结果得到证实。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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