Clinical Profile of Liver Cirrhosis at a Rural Tertiary Care Centre in Dhauladhar Region

S. Sharma, B. Rana
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Abstract

Background and aim: Epidemiology of liver cirrhosis suggests that although Hepatitis B and C are still common in developing countries, alcohol related cirrhosis is increasing in countries like India. Rising trends in alcohol consumption in North India, makes it essential to analyse the influence of these changes on the clinical profile of liver cirrhosis. Therefore, we aimed to study 50 patients of cirrhosis of liver in Dhauladhar region. Methods: In this descriptive hospital-based study, 50 patients with evidence of liver cirrhosis diagnosed on history, imaging and investigations were included for a period of 12 months. Results: In our study, 72% patients aged between 40-60 years with a mean age was 50.4±10.1 years. Around 58% patients had CTP Class C disease suggesting advanced disease in our study. In our study, 88% patients were anemic. 74% had thrombocytopenia. 40% patients also had kidney dysfunction. Conclusion: Cirrhosis is common in the most productive age and they also have co-morbidities like anemia, thrombocytopenia, and renal dysfunction.
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达拉达尔地区农村三级保健中心肝硬化的临床概况
背景和目的:肝硬化的流行病学表明,尽管乙型和丙型肝炎在发展中国家仍然很常见,但在印度等国家,与酒精相关的肝硬化正在增加。印度北部酒精消费的上升趋势使得分析这些变化对肝硬化临床概况的影响至关重要。因此,我们拟对拉拉哈尔地区50例肝硬化患者进行研究。方法:在这项以医院为基础的描述性研究中,纳入了50例经病史、影像学和调查诊断为肝硬化的患者,时间为12个月。结果:在我们的研究中,72%的患者年龄在40-60岁之间,平均年龄50.4±10.1岁。在我们的研究中,约58%的患者患有CTP C级疾病,表明疾病进展。在我们的研究中,88%的患者贫血。74%患有血小板减少症。40%的患者还伴有肾功能障碍。结论:肝硬化常见于生育年龄,并伴有贫血、血小板减少、肾功能不全等合并症。
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