Additional criteria for stratifying the ischemic stroke risk in patients with atrial fibrillation and one non‑sex‑related point on the CHA 2 DS 2 ‑VASc scale

Abstract

determine identify the 2 DS scale, the of ischemic and one ex elated risk factor (RF) for thromboembolic on A study of a retrospective analysis of case reports of patients with of patients with and one additional to 2 of The by Medical history data, results of ECG, EchoCG and ultrasound duplex scanning of brachiocephalic arteries (USDS BCA) were analyzed. Results . The main group included 50 patients aged 62.5 69.25), of which were 32%; the reference group included 68 patients aged 62 (57.0; 64.0), of which 38.2% were women. The main group compared to the reference group had significantly higher incidences of permanent AF (48% vs 23.9%; EchoCG signs of LV hypertrophy (LVH) (68% vs 44.1%; and thickened intima‑media complex (IMC) >0.9 mm as shown by USDS BCA (68% vs 22.1%; The monofactorial analysis demonstrated a significant increase in risk for ischemic stroke in the presence of permanent AF (HR, 2.552; 95% CI from 1.233 to 5.281), EchoCG evidence of LVH (HR, 2.673; 95% CI from 1.252 to 5.709), and thickened IMC (HR, 5.536; 95% CI from 2.643 to 11.594). Conclusion . Data of EchoCG and USDS BCA and the AF type should be taken into account in evaluating the risk for ischemic stroke and considering administration of oral anticoagulants for patients with AF and one additional to sex CHA 2 DS 2 ‑VASc RF who have non‑absolute indications for anticoagulant therapy.