Combined treatment modality for invasive ocular surface squamous neoplasia in an HIV positive patient: a case report

Abstract

Squamous cell carcinoma is an invasive type of ocular surface squamous neoplasia which is a term introduced for premalignant and malignant epithelial lesions from conjunctiva and cornea. Treatment outcome of ocular surface squamous neoplasia (OSSN) depends on its type and stage, which is confirmed by histopathological examination. Invasive type of OSSN as squamous cell carcinoma needs combined treatment to reduce its recurrence. We present a case of a 45 year old female patient with positive HIV status, presenting to our outpatient clinic with a progressive limbal mass. She underwent combined treatment modality with total excision along with cryo-application and topical mitomycin-C drops with no evidence of recurrence on follow-up for a year. Emphasis on various adjunctive therapies along with the surgical approach is also discussed.