Multiphoton optical biopsy

C. Dong, Wen Lo, Yen Sun, S. Teng, Yuan Liu, Hsuan-Shu Lee, Hsiao-Ching Chen, L. Chiou, Guan-Tarn Huang, Sung-Jan Lin, S. Jee, H. Tan, Wei-Chou Lin
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引用次数: 1

Abstract

Multiphoton microscopy is to a powerful imaging modality in the life sciences. The improved image contrast, greater imaging depths, and focus limited photodamage enable multiphoton microscopy to be especially useful for in vivo bioimaging applications. For multiphoton microscopy to be widely applicable in for in vivo biopsy applications, characterization of the tissues of interest must first be performed ex vivo. This presentation is an overview of the microscopic and spectroscopic characterization of the tissue types being pursued by my group. Both multiphoton images and spectroscopic information of a diverse range of normal, damaged, or diseased tissues will be presented and the implications of our results discussed.
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多光子光学活检
多光子显微镜是生命科学中一种强大的成像方式。改进的图像对比度、更大的成像深度和聚焦受限的光损伤使多光子显微镜在体内生物成像应用中特别有用。为了使多光子显微镜广泛应用于活体活检,必须首先在体外进行感兴趣组织的表征。本报告概述了我的小组正在研究的组织类型的显微和光谱特征。多光子图像和光谱信息的不同范围的正常,受损或病变组织将提出和我们的结果讨论的意义。
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