{"title":"[The effect of the spleen on tumor growth in mouse lines with various spleen sizes].","authors":"H von Wallenberg, P Mainusch, J Meyer, C Hammer","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Selectively raised laboratory mice differ according to spleen size in their immunologic behavior against various tumors. A small spleen and splenectomy reduce tumor growth, whereas a large spleen or additional transfer of tumor antigen-specific spleen cells (\"suppressor cells\") stimulate tumor incidence.</p>","PeriodicalId":75704,"journal":{"name":"Chirurgisches Forum fur experimentelle und klinische Forschung","volume":" ","pages":"169-73"},"PeriodicalIF":0.0000,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chirurgisches Forum fur experimentelle und klinische Forschung","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Selectively raised laboratory mice differ according to spleen size in their immunologic behavior against various tumors. A small spleen and splenectomy reduce tumor growth, whereas a large spleen or additional transfer of tumor antigen-specific spleen cells ("suppressor cells") stimulate tumor incidence.
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