Comparison of chosen clinical markers in patients with type 2 diabetes mellitus and latent carbohydrate metabolism disorders

Abstract

During the last 25 years growing epidemic of type 2 diabetes mellitus is observed. Full symptomatic clinical phase is followed by latent carbohydrate disturbances usually lasting for many years before and systematically intensifying during the time. Early diagnosis and treatment could lower the frequency of vascular complications, determined in most diabetic patients at the moment of diagnosis (1-3). Diabetes mellitus is a chronic disease of metabolic dysrégulation. The main characteristic feature of this disease is hyperglycemia which causes different pathologies in most of body organs. Common manifestations of long-term hyperglycemia are: neuropathy - nervous system damage and vascular diseases (2, 3). The aim of this study was to determine differences of chosen clinical markers in groups of patients with latent carbohydrate disorders, previously diagnosed diabetes mellitus and long-term type 2 diabetes.