Modeling cochlear micromechanics: hypotheses and models

Abstract

The cochlea plays an important role in the mammalian auditory system. Sound-induced cell motion in the cochlea is transformed into electrical signals that are then sent to primary auditory neurons. The most significant feature of the cochlea is the active and nonlinear amplification of faint sounds. This active process cannot be explained via a simple hydromechanical representation of the cochlea, that is, a macromechanic explanation. Although the mechanisms of this amplification are not well understood, cochlear micromechanical behavior is thought to play a significant role. The measurement of in vivo cochlea micromechanical responses is challenging and restricted by technical limitations. Modeling the micromechanics of the cochlea, however, can facilitate the interpretation of experimental observations. In this paper, we reviewed studies in which researchers modeled the cochlear micromechanics, and we discussed various modeling hypotheses, outcomes, and expectations. Key words: auditory; cochlea; cochlear amplifier; cochlear micromechanics; cochlear macromechanics; cochlear models; modeling hypothesis; model validation