Genetic algorithm for edge extraction of glomerulus area

Jun Zhang, Hong Zhu, Xueming Qian, Tao Huang
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引用次数: 7

Abstract

The automatic analysis of kidney-tissue image is an important subsystem in the computer aided diagnosis system of kidney disease. In this subsystem, the correct extraction of glomerulus is an important premise to the exact analysis of kidney-tissue image. A glomerulus edge extraction method based on genetic algorithm (GA) is proposed by considering complex characteristics of the image. Firstly, different scale binary images are obtained by adjusting the parameters of LOG filter. Secondly, the crude spline curve fitting for the glomerulus area boundary is got by genetic algorithm based on the small-scale binary image. Thirdly, elaborate adjustment of spline fitting curve is performed according to more boundary information of large-scale binary image to get the optimal spline curve. Finally, the glomerulus area can be extracted correctly according to the fitting curve. Experimental result indicates high precision of glomerulus edge extraction from the kidney-tissue image.
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基于遗传算法的肾小球区域边缘提取
肾脏组织图像自动分析是肾脏疾病计算机辅助诊断系统的一个重要子系统。在该子系统中,正确提取肾小球是准确分析肾组织图像的重要前提。考虑图像的复杂特征,提出了一种基于遗传算法的肾小球边缘提取方法。首先,通过调整LOG滤波器的参数,得到不同尺度的二值图像;其次,基于小尺度二值图像,采用遗传算法对肾小球区域边界进行粗样条曲线拟合;第三,根据大尺度二值图像的更多边界信息,对样条拟合曲线进行精细调整,得到最优样条曲线;最后根据拟合曲线正确提取肾小球面积。实验结果表明,从肾组织图像中提取肾小球边缘具有较高的精度。
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