Image driven cell manipulation using optical dielectrophoresis (ODEP)

Abstract

We demonstrated a novel approach to trigger the dielectrophoretic force to manipulate biological cells via projected flash images. The attractive and repulsive force regions are formed due to effectively initiated dielectrophoretic force, where these regions are the bright and dark area among a projected image on a liquid reservoir depending on the polarization states. In present study, the attractive force draw in live cells, saccharomyces cerevisiae, and live cells can be manipulated inside reservoir without any microchannel confinement in a programmable manner. The relation between distance from the boundary and average velocity is also discussed.