Lifelog-based classification of mild cognitive impairment using artificial neural networks

Sang-ho Lee, Won-Seok Kang, C. Moon
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Abstract

The swift diagnosis and treatment of mild cognitive impairment (MCI), as a prestage of dementia, are important to reduce the enormous costs of dementia treatment. The aim of this paper is to investigate the potential features in human behavior to facilitate the early diagnosis of MCI. In order to extract specific features from lifelogs, we collected data of activity and sleep using Fitbit's wrist band worn day and night from 12 subjects, for 12 week each. These data were analyzed using the SPSS (Statistical Package for Social Science) for verification and 12 total numbers of the significant features are extracted, further these features used for classification based on artificial neural networks (ANNs). ANNs with 8 input neurons (extracted features), 4 hidden neurons, and output neurons (diagnosis) were used to classify the patients. The results indicate that lifelog-based classifier have a good capacity (AUC=0.81 ±0.08) to discriminate MCI patients from healthy controls.
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基于生活日志的轻度认知障碍人工神经网络分类
快速诊断和治疗轻度认知障碍(MCI)作为痴呆症的前期阶段,对于降低痴呆症治疗的巨大成本至关重要。本文的目的是探讨人类行为的潜在特征,以促进MCI的早期诊断。为了从生活日志中提取特定的特征,我们使用Fitbit的腕带收集了12名受试者的活动和睡眠数据,每个人佩戴12周。使用SPSS (Statistical Package for Social Science)对这些数据进行分析验证,并提取出12个显著特征,进一步将这些特征用于基于人工神经网络(ann)的分类。使用8个输入神经元(提取特征)、4个隐藏神经元和输出神经元(诊断)的神经网络对患者进行分类。结果表明,基于生命记录的分类器对MCI患者与健康对照有较好的鉴别能力(AUC=0.81±0.08)。
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