Anti inflammatory effect of methanolic extract of Hedyotis Umbellata Linn

Abstract

Objective: To explore anti-inflammatory activity of Hedyotis umbellata Linn.Method : Anti inflammatory activity of methanol extract of aerial parts of Hedyotis Umbellata (MEHU) Linn was studied using Carrageenan induced paw edema model. MEHU reduced paw edema significantly (P<0.05) at 250 mg/kg and 500 mg/kg. Diclofenac sodium was included as standard. Report: MEHU at 250 mg/kg and 500 mg/kg produced significant (P<0.05) reduction on paw edema induced by carrageenan. The activity also comparable to the standard anti-inflammatory agent Diclofenac sodium.Conclusion: From the findings we conclude that Hedyotis umbellata possess antiinflammatory activity.