Analysis of dynamic characteristics of rugged vessel in the process of hepatic perfusion

Abstract

The paper attempts to analyze the dynamic characteristics in the perfusion process of the hepatic vessel. A model of rugged vessel with a foreign matter was established based upon medical imaging data. The fluid flowing in the rugged vessel was simulated using the perfusion method of the symmetric pulsating flow (SPF) and the steady flow under the bidirectional fluid-structure interaction (FSI). The simulation results, on the one hand, demonstrate the feasibility of SPF within the perfusion process of the rugged vessel in liver. On the other hand, the results clearly show the dynamic behaviors which accorded with actual medical results. Comparing the perfusion results of the rugged vessel using SPF with the steady flow, the difference of vascular deformation is not obvious, while the peak of velocity in the rugged vessel used SPF is about 50% higher than that of the steady flow, that reveals SPF is more likely to take away the foreign matter. The study will be helpful to improve the quality of the donor liver and reduce the influence of subjective factors on the quality of cleaning, and it provides theoretical basis for the liver transplantation.