The Complete Blood Count Modified Results in Patients with Complicated Colorectal Cancer

Abstract

Introduction: Among the factors on which the long-term survival of patients with colorectal cancer depends, the biological status at admission is essential and it is well reflected by a simple, routine analysis: The complete blood count (CBC). The link between the values of the hemoleukogram parameters and the diagnosis of colorectal cancers, but also between the changes in the hemoleukogram and the prognosis of patients with colorectal cancer is well documented in the literature. The aim of this study is to show the link between CBC changes at admission and the survival of patients with complicated colorectal cancer. Patients and methods: We conducted a retrospective study that included 431 patients admitted and operated in emergency for complicated colorectal cancer, in the Surgery II Clinic of the Clinical Emergency County Hospital “St. Ap. Andrei” from Galati between 2008-2017. We made statistical correlations between the 4 types of emergency operations (external derivations, Hartmann, internal derivations and resections with anastomosis) and CBC changes, as well as a survival analysis depending on the presence of these changes. Results: The presence of anemia at admission is statistically significant correlated with the practice of emergency colostomies and the presence of leukocytosis is correlated with Hartmann operations. In our study, only the anemia was a negative prognostic factor for the long-term survival of patients with complicated colorectal cancer. Conclusions: The complete blood count is a routine, simple, cost-effective laboratory test that can be a very useful tool in assessing the prognosis of patients with complicated colorectal cancer. as well as a survival analysis depending on the presence of these changes.