REVIEW ON PLANT TISSUE CULTURE: A SOURCE OF PHYTO-PHARMACEUTICALS

Harjeet Singh, Gagandeep Singh, Charul Anand, G. Babu.
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Abstract

Since ancient times, plants have been used in the form of medicines in various traditional systems like Ayurveda, Unani, Homeopathy, Chinese and Siddha. Plants have been a potential source of natural products from various plant parts like root, stem, leaf and bark. Plants usually produce primary and secondary metabolites and use of plant tissue culture for production of secondary metabolites is quite common.The plant cells offer a novel route for the synthesis of a wide array of secondary metabolites, many of which are used as valuable drugs. Some of these are difficult to synthesize by conventional methods. The morphology and chemical totipotency of plant cells enables any cell of plant for the synthesis of compounds produced by the intact plant. The secondary metabolites on plant cell cultures can be significantly enhanced by elicitation, precursor feeding, media modification, hairy root culture, immobilization of plant cells, biotransformation or by manipulating culture conditions.
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植物组织培养:植物药物的来源
自古以来,植物就以药物的形式被用于各种传统系统,如阿育吠陀,乌纳尼,顺势疗法,中国和悉达。植物已成为各种植物部位(如根、茎、叶和树皮)天然产物的潜在来源。植物通常产生初级代谢物和次级代谢物,利用植物组织培养生产次生代谢物是很常见的。植物细胞为合成一系列次生代谢物提供了一条新途径,其中许多代谢物被用作有价值的药物。其中一些难以用常规方法合成。植物细胞的形态和化学全能性使植物的任何细胞都能合成完整植物所产生的化合物。诱导、前体饲喂、培养基修饰、毛状根培养、植物细胞固定化、生物转化或调节培养条件均可显著提高植物细胞培养物的次生代谢产物。
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