[Hypothermic storage under aerobic conditions--the effect of different flushing solutions on kidney functional recovery].

J H Fischer, M Miyata, W Isselhard, H R Casser
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引用次数: 0

Abstract

Canine kidneys (n = 17) were flushed with COLLINS (C2), SACKS II, LAMBOTTE (KMgS), ROSS (hypertonic citrate), or RINGER glucose-mannitol solution following a 30-min period of normothermic ischemia. After 24 h hypothermic preservation with retrograde oxygen persufflation (ROP) and autotransplantation, the immediate functional recovery was determined using inulin and PAH clearance methods and compared with the normal contralateral kidney. While a good functional recovery was found in the COLLINS group, significantly exceeding results from hypothermic ischemic storage preservation, in experiments using other flush solutions ROP preservation resulted in only a small immediate function. Thus the experiments indicate that COLLINS solution C2 is the optimal flush solution for ROP preservation.

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【有氧条件下低温贮藏——不同冲洗液对肾功能恢复的影响】。
在恒温缺血30分钟后,用COLLINS (C2)、SACKS II、LAMBOTTE (kmg)、ROSS(高渗柠檬酸盐)或RINGER葡萄糖-甘露醇溶液冲洗犬肾(n = 17)。低温保存24 h逆行氧灌注(ROP)和自体移植后,采用菊粉和多环芳烃清除法测定其功能恢复情况,并与正常对侧肾脏进行比较。虽然在COLLINS组中发现了良好的功能恢复,明显超过了低温缺血储存保存的结果,但在使用其他冲洗液的实验中,ROP保存只产生了很小的即时功能。因此,实验表明COLLINS溶液C2是保持ROP的最佳冲洗溶液。
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