Granular Cell Tumor of the Tongue: A Rare Case Presentation of a 14 Years Old Girl

M. Nacouzi
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Abstract

Granular cell tumor or Abrikossoff ’s tumor is an infrequent tumor that can arise in most organs, and especially in the ENT area. It is a usually benign neoplasm, that can lead to a misdiagnose of malignancy. It affects both sex, between the fourth and the sixth decade. We present in this report a case of a 14 years old girl with a slowly growing lesion on the right lateral border of the mobile tongue. The biopsy showed a proliferation of large cells with a granular cytoplasm that expressed two immunohistochemistry markers: CD68 and S100 antibodies. Surgical resection was completed with a one centimeter margin.The rare issue about this case is the age of presentation: the age of the patient is 14, whereas this tumor usually affects adult patients.
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舌颗粒细胞瘤:一例罕见的14岁女孩
颗粒细胞瘤或Abrikossoff肿瘤是一种罕见的肿瘤,可发生在大多数器官,特别是在耳鼻喉区。它通常是良性肿瘤,可导致误诊为恶性肿瘤。在40岁到60岁之间,它对两性都有影响。我们在此报告的情况下,一个14岁的女孩与一个缓慢增长的病变在右外侧边界的活动舌。活检显示有颗粒状细胞质的大细胞增生,表达两种免疫组织化学标记物:CD68和S100抗体。手术切除的边缘为1厘米。这个病例的罕见问题是出现的年龄:患者的年龄是14岁,而这种肿瘤通常影响成年患者。
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