{"title":"Predicting Breast Cancer Outcome under Different Treatments by Feature Selection Approaches","authors":"H. Pham, L. Rueda, A. Ngom","doi":"10.1145/3107411.3108226","DOIUrl":null,"url":null,"abstract":"Gene expression data have been used in many researches to help reveal the underlying mechanism of many diseases. In this study, we applied feature selection techniques on breast cancer patients in the METABRIC Study to predict whether patients will be disease free or not, under different treatments. Our models for prediction are of high performance, thus, the genes in those models might help reveal the mechanism of the disease, and these potential biomarkers can become targets for new therapies.","PeriodicalId":246388,"journal":{"name":"Proceedings of the 8th ACM International Conference on Bioinformatics, Computational Biology,and Health Informatics","volume":"148 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2017-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the 8th ACM International Conference on Bioinformatics, Computational Biology,and Health Informatics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1145/3107411.3108226","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Gene expression data have been used in many researches to help reveal the underlying mechanism of many diseases. In this study, we applied feature selection techniques on breast cancer patients in the METABRIC Study to predict whether patients will be disease free or not, under different treatments. Our models for prediction are of high performance, thus, the genes in those models might help reveal the mechanism of the disease, and these potential biomarkers can become targets for new therapies.