Kronik Obstrüktif Akciğer Hastalığında Noktürnal Noninvaziv Pozitif Basınçlı Ventilasyon

Özlem Özkan Kuşcu, Pınar Ergenoğlu
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Abstract

Chronic Obstructive Pulmonary Disease is characterized as a progressive and irreversible inflammatory response in the airways and alveoli because of exposure to noxious particles or gases. Excessive inflammation causes progressive, persistent, and not fully reversible structural changes and airflow limitation. Although COPD is a significant public health problem, diagnosis and treatment stages need to be improved.Nocturnal Noninvasive Positive Pressure Ventilation is one of the treatment modalities of choice for COPD exacerbation, and the role and benefits of NPPV in COPD exacerbation are well defined, but the use of nocturnal NPPV on stable severe COPD individuals is controversial, and the evidence is not sufficient yet. This review evaluates the effects of nocturnal NPPV on stable COPD patients.
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慢性阻塞性肺疾病的特征是由于暴露于有害颗粒或气体而在气道和肺泡中发生进行性和不可逆的炎症反应。过度炎症引起进行性、持续性和不完全可逆的结构改变和气流限制。虽然慢性阻塞性肺病是一个重大的公共卫生问题,但诊断和治疗阶段需要改进。夜间无创正压通气(NPPV)是COPD加重的首选治疗方式之一,NPPV在COPD加重中的作用和益处已明确,但在稳定期重度COPD患者中应用夜间NPPV存在争议,证据尚不充分。本综述评估夜间NPPV对稳定期COPD患者的影响。
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