Drug resistance among Mycobacterium tuberculosis strains isolated in Taiwan during 1975.

K H Hsu, T H Ueng, S T Hsu
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Abstract

455 strains of Mycobacterium tuberculosis were isolated from patients with history of treatment in Taiwan Provincial Tuberculosis Control Bureau and tested for resistance against various antituberculosis agents including streptomycin (SM), paraaminosalicylic acid (PAS), isoniazid (INH), cycloserine (CS), prothionamide (1321TH), kanamycin (KM), ethambutol (EMB), and rifampicin (RFP). In vitro resistance to SM and INH was more frequently found than others and the resistance to a single drug was more common than multiple resistance.

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1975年台湾分离结核分枝杆菌菌株的耐药性。
从台湾省结核病防控局有治疗史的患者中分离出455株结核分枝杆菌,检测其对链霉素(SM)、对氨基水杨酸(PAS)、异烟肼(INH)、环丝氨酸(CS)、丙硫酰胺(1321TH)、卡那霉素(KM)、乙胺丁醇(EMB)、利福平(RFP)等多种抗结核药物的耐药性。体外对SM和INH的耐药较常见,单药耐药较多重耐药多见。
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