The Surgical Learning Curve for Prostate Cancer Control After Radical Prostatectomy

P. Dahm
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Abstract

This chapter summarizes an important study exploring the learning curve of surgeons performing open radical prostatectomy with clinically localized prostate cancer. The study retrospectively analyzed a large cohort of patients from several major medical centers who underwent surgery by several dozen surgeons with varying experience with regards to the outcome of freedom from biochemical recurrence. The study found a dramatic improvement in cancer control with increasing surgeon experience up to 250 prior operations but no large change with further surgeon experience. This study stands out as the first large, high-quality study in the urological literature to provide a detailed analysis of the association of surgical experience with an important clinical outcome measure. It provided compelling evidence that surgical experience with prostatectomy results in improved oncological outcomes.
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根治性前列腺切除术后前列腺癌控制的手术学习曲线
本章总结了一项重要的研究,探讨了外科医生对临床局限性前列腺癌进行开放性根治性前列腺切除术的学习曲线。该研究回顾性分析了来自几个主要医疗中心的大量患者,这些患者接受了数十名外科医生的手术,这些外科医生在消除生化复发方面的经验各不相同。研究发现,随着外科医生经验的增加,癌症控制有了显著的改善,最多可达250次以前的手术,但随着外科医生经验的增加,没有太大的变化。这项研究是泌尿学文献中第一个大型、高质量的研究,提供了手术经验与重要临床结果测量之间关系的详细分析。它提供了令人信服的证据,前列腺切除术的手术经验可以改善肿瘤预后。
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