Effects of Young Barley Leaf Powder on Defecation Frequency and Fecal Characteristics of Healthy Volunteer

Motoya Ikeguchi, M. Kobayashi, Y. Ariura, Sadao Mori, Kinya Takagaki, Y. Ishibashi, Y. Sugawa-Katayama
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引用次数: 3

Abstract

The effects of young barley leaf powder(YBLP) on defecation frequency and fecal characteristics were studied in 61 healthy volunteers(34.1 •} 10.2 years old). The subjects were divided at random into 4 groups;non-dose control group(CG), low-dose group(LG), middle-dose group(MG), and high-dose group(HG). Total examination period was 4 weeks. After one week as the pre-test period, all groups were given a placebo diet for one week(placebo period). For the following 2 weeks(test period), CG, LG, MG and HG was given a placebo diet(not contained YBLP), a low-dose diet(1.5 g), a middledose diet(4.5 g) and a high-dose diet(6.0 g), respectively. In analysis, the subjects were screened under the condition that defecation frequency was below 7 times for one week of the pre-test period. This result showed that MG increased the defecation frequency and estimated fecal quantity significantly for the test period compared with those for the pre-test period, and HG increased them significantly for the test period compared with those for the pre-test period and placebo period. No clinical signs of toxicity recognized in the test period. These results suggest that YBLP has a fecal bulking effect and is useful for safety food material.
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青稞叶粉对健康志愿者排便频率及粪便特征的影响
研究了青稞叶粉(YBLP)对61名健康志愿者(34.1•}10.2岁)排便频率和粪便特征的影响。将受试者随机分为4组:非剂量对照组(CG)、低剂量组(LG)、中剂量组(MG)、高剂量组(HG)。总检查周期为4周。前测期1周后,各组均给予安慰剂饮食1周(安慰剂期)。在接下来的2周(试验期),CG、LG、MG和HG分别给予安慰剂饮食(不含YBLP)、低剂量饮食(1.5 g)、中剂量饮食(4.5 g)和高剂量饮食(6.0 g)。在分析中,受试者在测试前一周排便次数低于7次的条件下进行筛选。结果表明,MG组测试期排便次数和预估排便量较测试前显著增加,HG组测试期排便次数和预估排便量较测试前和安慰剂组显著增加。试验期间未发现临床毒性症状。这些结果表明,YBLP具有粪便膨胀效应,可用于安全食品材料。
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