Surgical Therapy of Hepatocellular Carcinoma: State of the Art Liver Resection

S. Davakis, M. Vailas, Alexandros Kozadinos, P. Sakarellos, A. Karampa, D. Korkolis, G. Glantzounis, Alexandros Papalampros, E. Felekouras
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Abstract

Hepatocellular carcinoma (HCC) represents the third most common cause of cancer-related death, showing incremental growth rates throughout the last decades. HCC requires multidisciplinary approach in a group of patients suffering from underlying chronic liver disease, usually in the setting of cirrhosis. The mainstay of treatment in resectable cases is surgery, with anatomic and non-anatomic liver resections widely implemented, as well as liver transplantation in well-selected individuals. Nowadays, there is a variety of liver parenchyma transection devices used by hepatobiliary surgeons in specialized centers, which has significantly improved postoperative outcomes in HCC patients. Therefore, hepatectomy is considered safe and feasible and should be the main therapeutic option for HCC patients, candidates for resection. Liver resection utilizing cavitron ultrasonic aspirator in combination with bipolar radiofrequency ablation is safe and effective for the treatment of HCC with favorable clinical and oncological outcomes.
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肝细胞癌的外科治疗:肝切除术的现状
肝细胞癌(HCC)是癌症相关死亡的第三大常见原因,在过去几十年中呈现出递增的增长速度。肝细胞癌需要多学科联合治疗,治疗一组患有潜在慢性肝病的患者,通常伴有肝硬化。可切除病例的主要治疗方法是手术,解剖和非解剖性肝切除术广泛实施,以及在精心挑选的个体中进行肝移植。目前,专业中心的肝胆外科医生使用了多种肝实质横断装置,显著改善了HCC患者的术后预后。因此,肝切除术被认为是安全可行的,应该是HCC患者的主要治疗选择,是切除的候选者。空腔超声吸引器联合双极射频消融术治疗肝细胞癌安全有效,临床及肿瘤预后良好。
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