Rationale and Design of Two, Phase 3, Randomized Controlled Trials (COUGH-1 and COUGH-2) of Gefapixant, A P2x3 Receptor Antagonist, in Refractory and Unexplained Chronic Cough

D. Muccino, A. Morice, S. Birring, L. Mcgarvey, P. Dicpinigaitis, I. Pavord, A. Tershakovec, M. Kitt, Y. Zheng, C. Assaid, Jacky A. Smith
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P2x3受体拮抗剂Gefapixant治疗难治性和不明原因慢性咳嗽的两项3期随机对照试验(cough1和cough2)的基本原理和设计
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BLU-5937 a Highly Selective P2X3 Homotrimeric Receptor Antagonist with Improved Taste Safety Profile in Healthy Subjects Characterization of Patients with Obstructive Lung Disease in the NOVEL Observational LongiTudinal StudY, NOVELTY Chronic Cough: Differences in Characteristics Between Obese and Non Obese Subjects Pleural Fluid Factors Associated with Tunneled Pleural Catheter Related Pleurodesis Rationale and Design of Two, Phase 3, Randomized Controlled Trials (COUGH-1 and COUGH-2) of Gefapixant, A P2x3 Receptor Antagonist, in Refractory and Unexplained Chronic Cough
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